About Health commons

Solving the Health Research Puzzle

Imagine a virtual marketplace or ecosystem where participants share data, knowledge, materials and services to accelerate research. The components might include databases on the results of chemical assays, toxicity screens, and clinical trials; libraries of drugs and chemical compounds; repositories of biological materials (tissue samples, cell lines, molecules), computational models predicting drug efficacies or side effects, and contract services for high-throughput genomics and proteomics, combinatorial drug screening, animal testing, biostatistics, and more.

We envision a Commons where a researcher will be able to order everything needed to replicate a published experiment as easily as ordering DVDs from Amazon, where where one can create a workflow to exploit replicated results on an industrial scale.

Health Commons’ marketplace will slash the time, cost, and risk of developing treatments for diseases. Individual researchers, institutions, and companies will be able to publish information about their expertise and resources so that others in the community can readily discover and use them. Core competencies, from clinical trial design to molecular profiling, will be packaged as turnkey services and made available over the Net. The Commons will serve as the public-domain, non-profit hub, with third-parties providing value added services that facilitate information access, communication, and collaboration.

Health Commons is a coalition of parties interested in changing the way basic science is translated into the understanding and improvement of human health. Coalition members agree to share data, knowledge, and services under standardized terms and conditions by committing to a set of common technologies, digital information standards, research materials, contracts, workflows, and software. These commitments ensure that knowledge, data, materials and tools can move seamlessly from partner to partner across the entire drug discovery chain. They enable participants to offer standardized services, ranging from simple molecular assays to complex drug synthesis solutions, that others can discover in directories and integrate into their own processes to expedite development — or assemble like LEGO blocks to create new services.

The Health Commons is too complex for any one organization or company to create. It requires a coalition of partners across the spectrum. It is also too complex for public, private, or non-profit organizations alone - reinventing therapy development for the networked world requires, from the beginning, a commitment to public-private partnership. Only through a public-private partnership can the key infrastructure of the Commons be created: the investments in the public domain of information and materials will only be realized if that public domain is served by a private set of systems integrators and materials, tools and service providers motivated by profit. And in turn, the long-term success of the private sector depends on a growing, robust, and self-replenishing public domain of data, research tools, and open source software.


Read The White Paper »

 

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our principles

"Some Rights Reserved"

In order for network effects - like those that have transformed culture and commerce - to benefit the health research and delivery system, we need to use the methods of a digital commons to create a standardized balanced between all rights reserved and no rights reserved. Sharing needs to be easy, legal, and scaleable. Creative Commons has shown that "some rights reserved" approaches simply work better on the network than many traditional approaches, and brings that expertise to the project.

"Open Source Integration"

Integration of complex content like data, workflows, service descriptions, ontologies, biological materials, and similar components of health research requires that we all work together. Even major pharmaceutical companies can't do it alone. Open source methodologies give us a powerful tool to leverag the power of the community, and to turn scale from a problem into an asset.

"Network Biology = Open Access Biology"

Knowledge wants to form networks, and networks work best when they're based on open standards. Disease biology is rapidly becoming network biology and will become a pre-competitive space. Pharmaceutical companies and academic groups cannot afford to assemble these data sets on their own, and the data, expertise, knowledge, tools, and compounds are simply too fragmented to allow the networks to be specified and integrated. Access to public information in "re-useful" formats is an essential precondition of network biology.

"Enable One-Click"

Even as we have seen systems like Amazon and eBay emerge - that move physical goods around the world, thanks to the network - those benefits have failed to emerge for the sciences. A networked system of locks has kept the network from transforming the way we share scientific materials. A more efficient, higher throughput materials transfer system can be created and used to achieve greater public benefit. Return on investment in biological research demands that we reduce the need to reinvent existing wheels.

The Health Commons is a joint project of:

CollabRx

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Creative Commons

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CommerceNet

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Public Library of Science

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